What is the catalog number for NLG919?

The catalog number for NLG919 is bs-82923C.

What sizes are available for NLG919?

NLG919 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does NLG919 come in?

NLG919 is available in 2 different pack sizes.

NLG919 is currently made to order / not held in immediate stock. Contact us for lead time.

NLG919

Product Specifications

Background

NLG919 (1402836-58-1) is a potent IDO-pathway inhibitor (Ki = 7nM; EC50 = 75nM) .1 It synergizes with chemo-radiation therapy to promote T cell dependent complement deposition in a murine model of glioblastoma.2 In combination with paclitaxel in a mouse B16-F10 melanoma model, NLG919 increased the percentage of CD3+, CD8+, and CD4+ T cells and secretion of IFN-γ and interleukin-2 while decreasing the percentage of CD4+CD25+ regulatory T cells.3