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7alpha-Hydroxycholesterol

Product Specifications

Background

Metabolite resulting from the action of cholesterol 7 alpha-hydroxylase on cholesterol. 7α-Hydroxycholesterol is the first intermediate and a rate-limiting step in the major pathway for bile acid synthesis in humans. A pro-inflammatory mediator which upregulates production of CCL2 and MMP9 in macrophages and may promote progression of atherosclerosis.2,3 Possible biomarker for cellular lipid peroxidation.4

Conjugation

Unconjugated

Buffer

White or pale yellow solid

Storage Conditions

-20°C

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-82904C

Available Sizes

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