What is the catalog number for SR1078?

The catalog number for SR1078 is bs-82783C.

What sizes are available for SR1078?

SR1078 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does SR1078 come in?

SR1078 is available in 2 different pack sizes.

SR1078 is currently made to order / not held in immediate stock. Contact us for lead time.

SR1078

Product Specifications

Background

Agonist of the orphan nuclear receptors RORα and RORγ.1 It attenuated intrapancreatic pathological changes in mouse models of chronic pancreatitis via restoration of the circadian stabilizing loop.2 SR1078 stimulation of RORα restored clock protein BMAL1 expression and oscillation and blocked MYCN-mediated neuroblastoma growth.3 It reduced repetitive behavior is a mouse model of autism suggesting a potential therapeutic pathway for the disorder.4 SR1078 treatment lead to an increase in p53 levels and increased apoptosis in HepG2 cells.5