A-438079 HCl
Product Specifications
Background
A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9) .1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1ß and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3 It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1395891 Inquire
Recombinant Torque teno douroucouli virus Capsid protein (ORF1), partial
Sign In for Pricing
View Details