SGC-iMLLT
Product Specifications
Background
Potent (IC50 = 260 nM) inhibitor of the YEATS domain of MLLT1/3.1 YEATS domain containing proteins bind acetyl and crotonyl marks on histone tails. Selective against the two other human YEATS domains YEATS2/4 and 48 bromodomains. YEATS containing MLL-ENL leukemic cells display increased sensitivity to SGC-iMLLT versus control AML cells.2
Conjugation
Unconjugated
Buffer
Off-white to beige solid
Storage Conditions
-20°C
Available Sizes
Curated Selection
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