EED-226
Product Specifications
Background
EED-226 is a potent (IC50 = 23.4 nM) and selective allosteric inhibitor of the EED subunit of the methyltransferase polycomb repressive complex 2 (PRC2) .1,2 It caused drastic proliferation inhibition in lymphoma cells with EZH2 mutations and caused shrinkage and slower tumor growth in mice using a subcutaneous xenograft model of Karpas422.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C
Available Sizes
Curated Selection
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