MPEP HCl
Product Specifications
Background
MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5) .1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinson’s3,4, Fragile X syndrome5, and addiction6.
Conjugation
Unconjugated
Buffer
White or pale yellow solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC681076-500 1x 500 µL
Cytokeratin, HMW (KRTH/1076), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details ![CD32A + CD32B + CD32C Recombinant Rabbit Monoclonal Antibody [JE64-17]](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea816cd/imageurl/ha721930.webp)
HA721930 100 µL
CD32A + CD32B + CD32C Recombinant Rabbit Monoclonal Antibody [JE64-17]
Sign In for Pricing
View Details 
