Elafibranor
Product Specifications
Background
Elafibranor is a dual PPARalpha/delta agonist (EC50 PPARalpha = 10-20 nM; PPARdelta = 100-150 nM) .1 It was able to decrease plasma triglycerides levels1, increase HDL cholesterol levels in human studies1, and improve hepatic and peripheral insulin sensitivity2. Elafibranor’s antidiabetic effects in db/db were without the adverse cardiac effects seen in PPARgamma agonism.3 Elafibranor has also been shown to have therapeutic promise in the treatment of nonalcoholic steatohepatitis (NASH) .4-6
Conjugation
Unconjugated
Buffer
Pale yellow solid
Storage Conditions
-20°C
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-82719C
Available Sizes
Curated Selection
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