CD16 Antibody

Mouse monoclonal antibody to CD16 which expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts. It is a receptor for the Fc region of IgG. CD16 is one of only four eukaryotic receptors known to exist natively in both the transmembrane and glycosylphosphatidylinositol isoforms.

Product Specifications

Product Name Alternative

FcgammaRIII, IGFR3, FCRIII

Reactivity

Human, Primate

Immunogen

Human neutrophils

Target

CD16

Clonality

Monoclonal

Clone

3G8

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Functional application: In vitro stimulation of NK cell proliferation, blocking of IgG binding and phagocytosis, inhibition of cytotoxic activity, in vivo NK cell depletion. Flow cytometry: Recommended dilution: 6 μg/ml. Immunohistochemistry (frozen sections) : Acetone fixation.