What is the catalog number for AA43279?

The catalog number for AA43279 is bs-82687C.

What sizes are available for AA43279?

AA43279 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does AA43279 come in?

AA43279 is available in 2 different pack sizes.

AA43279 is currently made to order / not held in immediate stock. Contact us for lead time.

AA43279

Product Specifications

Background

Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 µM) . In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1