AA43279
Product Specifications
Background
Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 µM) . In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
Conjugation
Unconjugated
Buffer
Tan solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
130838-ML490 100 µL
PAICS (ADE2, AIRC, PAIS, Multifunctional Protein ADE2, AIR Carboxylase, SAICAR Synthetase, Phosphoribosylaminoimidazole-succinocarboxamide Synthase, Phosphoribosylaminoimidazole Carboxylase) (MaxLight 490)
Sign In for Pricing
View Details 
MBS6002822-01 0.2 mL
EIF3CL, NT (EIF3C, EIF3S8, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit 8, eIF3 p110)
Sign In for Pricing
View Details MBS6002822-02 5x 0.2 mL
EIF3CL, NT (EIF3C, EIF3S8, Eukaryotic translation initiation factor 3 subunit C, Eukaryotic translation initiation factor 3 subunit 8, eIF3 p110)
Sign In for Pricing
View Details 
bs-13320R-APC-Cy5.5 100 µL
GCP4 Polyclonal Antibody, APC-Cy5.5 Conjugated
Sign In for Pricing
View Details