CLP-3094
Product Specifications
Background
GPR142 is highly expressed in the pancreas and immune system and shares 33% homology with GPR1391. Endogenous agonists identified to date include aromatic amino acids such as tryptophan and phenylalanine2. CLP-3094 was identified as a potent and selective GPR142 antagonist with an IC50=2.3 M against 1 mM L-tryptophan. It inhibited insulin secretion from islets induced by L-tryptophan and other agonists and displayed anti-inflammatory activity in a mouse arthritis model.3
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC741560-100 1x 100 µL
Angiotensin I Converting Enzyme (ACE) / CD143 (9B9), CF740 conjugate, 0.1mg/mL
Sign In for Pricing
View Details A01246-2-Dylight550 100 µg
Anti-Occludin/OCLN Antibody Picoband®, Dylight550 Conjugate
Sign In for Pricing
View Details 