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Flavopiridol HCl

Product Specifications

Background

Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.

Conjugation

Unconjugated

Buffer

Light yellow solid

Storage Conditions

-20°C

Available Sizes

Curated Selection

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