Kenpaullone
Product Specifications
Background
Inhibits GSK-3β (IC50=0.23 µM) as well as several cyclin-dependent kinases (CDKs), IC50=0.4, 0.68 and 0.85 µM for cdk1, cdk2 and cdk5 respectively.1-3 Induces pluripotent stem cells from somatic cells4 and increases direct neural conversion of human fibroblasts5 when used with other small molecules. Inhibits Kruppel-Like Factor 4 (KLF4) reducing autoimmune arthritis in the collagen-induced arthritis mouse model.6
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C
Available Sizes
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