What is the catalog number for PAC-1?

The catalog number for PAC-1 is bs-82621C.

What sizes are available for PAC-1?

PAC-1 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does PAC-1 come in?

PAC-1 is available in 2 different pack sizes.

PAC-1 is currently made to order / not held in immediate stock. Contact us for lead time.

PAC-1

Product Specifications

Background

PAC-1 is a procaspase-activating compound, directly activating procaspase-3, producing caspase-3, EC50=0.22 μM.1 It is less potent at activating procaspase-7, EC50=4.5 μM. It induces apoptosis in a variety of cancer cell lines. The mechanism of activation involves sequestering inhibitory zinc ions thus allowing procaspase-3 to autoactivate.2 Sensitizes cancer cells to various chemotherapeutic agents.3