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CD64 Antibody

Mouse monoclonal antibody to CD64 which is a glycoprotein that is constitutively expressed on human monocytes and macrophages. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity and also acts in mediating humoral immune responses.

Product Specifications

Product Name Alternative

FcRI, IGFR1, FcgR1A

UniProt

P12314

Reactivity

Human, Primate

Immunogen

Rheumatoid synovial fluid cells and fibronectin purified human monocytes

Target

CD64

Clonality

Monoclonal

Clone

10.1

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Functional application: Blocking of IgG binding to the FcγR1. Flow cytometry: Recommended dilution: 1-4 μg/ml. Immunohistochemistry (paraffin sections and frozen sections) : There can occur problems with paraformaldehyde fixation.

Tested Applications

FA, FC, ICC, IHC-Fr, IHC-P, IP, WB

Preservative

Phosphate buffered saline (PBS), pH 7.4

Isotype

Mouse IgG1 kappa

Entrez

2209

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