Obatoclax
Product Specifications
Background
A novel Bcl-2 homology domain-3 (BH3) mimetic1. Inhibits primary acute myeloid leukemia (AML) progenitor cell proliferation (IC50=0.18 μM) and induces apoptosis in primary AML cells (IC50= 3.6 μM) 2. Synergizes with other agents such as chloroquine3 and cytarabine4 in cytotoxicity against a variety of cancer cells.
Conjugation
Unconjugated
Buffer
Purple solid
Storage Conditions
-20°C
Available Sizes
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