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Monastrol

Product Specifications

Background

Potent, cell-permeable, small molecule inhibitor of mitosis. Monastrol-arrested cells are characterized by monopolar spindles.1 Does not affect other motor proteins or tubulin. Specifically inhibits the mitotic molecular motor kinesin Eg5, a motor protein required for spindle formation (IC50 = 14 μM) .2 Mimics the effect of amyloid β on long term potentiation in a cellular model of learning and memory.3 Enhances regeneration of adult axons.4

Conjugation

Unconjugated

Buffer

Beige solid

Storage Conditions

-20°C

Available Sizes

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