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Memantine HCl

Product Specifications

Background

An NMDA noncompetitive, low affinity, open channel blocker, IC50~1 μM at -60 mV in rat retinal ganglion cells.1 Displays neuroprotective effects in excitotoxic conditions.2 Preferentially blocks excessive NMDA receptor activity without disrupting normal activity.3 A clinically well tolerated drug with therapeutic potential in numerous CNS degenerative disorders.4 In clinical use for Alzheimer’s disease.5

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

RT

Available Sizes

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