Erlotinib · HCl
Product Specifications
Background
Potent inhibitor of EGFR tyrosine kinase (IC50 = 2 nM) 1. Potent inhibitor of mutant JAK2-V617F2. Weaker inhibitor of ErbB-2 kinase (Ki = 1 μM) ErbB-4 kinase (Ki = 1.5 μM) 3. HDAC inhibitors sensitize for erlotinib activity in EGFR-mutated and wildtype non-small cell lung cancer (NSCLC) cells4. A clinically effective agent for NSCLC5.
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Human SULT1E1 Matched Antibody Pair Set [Poly/Poly] (Z01LS-1122-LS271)](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
Z01LS-1122-LS271 5 Plates
Human SULT1E1 Matched Antibody Pair Set [Poly/Poly] (Z01LS-1122-LS271)
Ask
View Details 302573-PE 200 µL
Msi1 (RNA-Binding Protein Musashi Homolog 1, Musashi-1, Msi1, Msi1h) (PE) discontinued
Ask
View Details ![Rabbit Polyclonal ATF6 Antibody [DyLight 755]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)