Erlotinib · HCl
Product Specifications
Background
Potent inhibitor of EGFR tyrosine kinase (IC50 = 2 nM) 1. Potent inhibitor of mutant JAK2-V617F2. Weaker inhibitor of ErbB-2 kinase (Ki = 1 μM) ErbB-4 kinase (Ki = 1.5 μM) 3. HDAC inhibitors sensitize for erlotinib activity in EGFR-mutated and wildtype non-small cell lung cancer (NSCLC) cells4. A clinically effective agent for NSCLC5.
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
GTR15361048 1 Vial
Lentiviral human RBFOX2 sgRNA gene knockout kit - Lentiviral human RBFOX2 sgRNA gene knockout kit (100)
Ask
View Details