Doramapimod
Product Specifications
Background
Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site.1 (IC50=18 nM) . Displays anti-inflammatory activity2 but differential effects on inflammatory genes3. Cell permeable.
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C
Available Sizes
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