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2',3'-cGAMP

Product Specifications

Background

2',3'-cGAMP (CAS 1441190-66-4) is an endogenous STING (stimulator of interferon genes) agonist.1 Produced from ATP and GTP via the action of cGMP-AMP synthase (cGAS) which acts as a cytosolic DNA sensor.2,3 Induces autophagy which is a mechanism for clearance of DNA and viruses in the cytosol.4 DNA damage stimulates 2’,3’-cGAMP which stimulates an inflammatory response.5

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

Available Sizes

Frequently Asked Questions

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