UCF-101
Product Specifications
Background
UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 μM for His-Omi134-458) . Shows very little activity against various other serine proteases tested (IC50 ≥ 200 μM) .1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.
Conjugation
Unconjugated
Buffer
Orange solid
Storage Conditions
-20°C
Available Sizes
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