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MitoBloCK-12

Product Specifications

Background

Attenuates mitochondrial protein import (4-10 M) . Discovered in a screen of FDA-approved drugs. Blocks translocation of a mutant form of alanine: glyoxylate aminotransferase (AGT) to the mitochondria and restores AGT trafficking to peroxisomes.1 Also reduces oxalate accumulation and thus has potential to treat patients with primary hyperoxaluria 1 who possess mutations in AGT.1 Also displays antimicrobial activity2, inhibits apamin-sensitive K+ channels3 and induces apoptosis by inhibiting XIAP4.

Conjugation

Unconjugated

Buffer

Beige solid

Storage Conditions

RT

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-82303C

Available Sizes

Curated Selection

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