HIF-2α-I2
Product Specifications
Background
Potent and selective HIF-2α inhibitor, Kd=81 nM.1 Binds to the HIF-2α PAS-B domain2 and interferes with Hif-2α / ARNT heterodimerization reducing target gene expression in a cellular model1. Highly selective for HIF-2α displaying a >60-fold selectivity over HIF-1α.1,2
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C
Available Sizes
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