YM-155
Product Specifications
Background
A novel small molecule survivin suppressant. YM-155 suppresses expression of survivin (a member of the IAP family) and induced apoptosis in human tumor cell lines at 10 nmol/L with little effect on other IAP or Bcl-2 family members.1 Overcomes erlotinib resistance in EGFR mutation-positive non-small cell lung cancer.2 Induces DNA damage.3 Induces an autophagy-dependent cell death in adenoid cystic carcinoma cells.4
Conjugation
Unconjugated
Buffer
Tan to yellow solid
Storage Conditions
-20°C
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
102600F0-AAT 100 Tests
IFluor® 647 Anti-mouse CD26 Antibody *H194-112*
Sign In for Pricing
View Details