What is the catalog number for AI-1?

The catalog number for AI-1 is bs-82266C.

What sizes are available for AI-1?

AI-1 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does AI-1 come in?

AI-1 is available in 2 different pack sizes.

AI-1 is currently made to order / not held in immediate stock. Contact us for lead time.

AI-1

Product Specifications

Background

A novel antioxidant response element (ARE) activator which activates Nrf2 by covalently modifying Keap1 (Kelch-like ECH-associated protein 1) a negative regulator of Nrf2. Modification of Cys151 of Keap1 by AI-1 disrupts the ability of Keap1 to searve as an adaptor for Cul3-Keap1 ubiquitin ligase complex, thereby stabilizing and inducing transcriptional activation of Nrf2. A useful pharmacological tool for probing the involvement of Nrf2 in cellular physiology1. Cell permeable.