What is the catalog number for NSC405020?

The catalog number for NSC405020 is bs-82259C.

What sizes are available for NSC405020?

NSC405020 is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does NSC405020 come in?

NSC405020 is available in 2 different pack sizes.

Is NSC405020 in stock?

NSC405020 is currently made to order / not held in immediate stock. Contact us for lead time.

NSC405020

Product Specifications

Background

Membrane type-1 matrix metalloproteinase (MMP14 or MT1-MMP) inhibitor that prevents homodimerization and inhibits MMP14’s protumorigenic activity in vivo. (IC50 > 100 μM) . Inhibition is via interaction with the hemopexin domain (PEX) of MMP14. NSC-405020 does not interfere with the catalytic activity of MT1-MMP or MMP-2. Suppresses bone erosion in a c-Fos-deficient mouse model.2 Decreases arsenic-mediated invasion of human squamous cell carcinoma HSC5 cells.3