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NSC632839

Product Specifications

Background

A pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway1,2. Cell permeable.

Conjugation

Unconjugated

Buffer

Yellow solid

Storage Conditions

-20°C

Available Sizes

Curated Selection

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