What is the catalog number for SMI-4a?

The catalog number for SMI-4a is bs-82198C.

What sizes are available for SMI-4a?

SMI-4a is available in the following size(s): 5 mg, 25 mg.

How many pack sizes does SMI-4a come in?

SMI-4a is available in 2 different pack sizes.

SMI-4a is currently made to order / not held in immediate stock. Contact us for lead time.

SMI-4a

Product Specifications

Background

A selective, ATP-competitive inhibitor of the Pim protein kinases (IC50 = 24 and 100 nM for Pim-1 and Pim-2 respectively) . Selective over a panel of ~50 other kinases1. Induces cell cycle arrest in leukemia and prostate cancer cells2. Blocks the growth of a wide range of myeloid and lymphoid cell lines with precursor T-cell lymphoblastic leukemia/lymphoma (pre-T-LBL/T-ALL) being highly sensitive3. A useful tool for exploring the involvement of Pim in cellular signaling4. Cell permeable.