Garcinol
Product Specifications
Background
Garcinol is a HAT (histone acetyltransferase) inhibitor (p300 IC50=7µM and PCAF IC50=5µM) both in vitro and in vivo.1 It potentiates TRAIL-induced apoptosis of cancer cells. Garcinol, independent of the cell type, induces both of the TRAIL receptors, death receptor 4 (DR4) and DR5. Garcinol neither induces the receptors of normal cells nor sensitizes them to TRAIL.2
Conjugation
Unconjugated
Buffer
Yellow solid
Storage Conditions
-20°C
Available Sizes
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