FH-535
Product Specifications
Background
Suppresses Wnt/β-catenin signaling. It antagonizes PPARγ and PPARδ ligand-dependent activation which is mediated by inhibition of recruitment of the coactivators β-catenin and GRIP1 but not the corepressors NCoR and SMRT1. Inhibits the migration and growth of breast cancer cell lines2 as well as colon, lung and liver cell lines1. Useful tool for probing the involvement of Wnt signaling pathway3,4.
Conjugation
Unconjugated
Buffer
Tan solid
Storage Conditions
-20°C
Available Sizes
Frequently Asked Questions
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