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Trifluorothymidine

Product Specifications

Background

An analog of thymidine which inhibits thymidylate synthase possesses antiviral and anticancer activity.1,2 After phosphorylation by thymidine kinase, it is incorporated into DNA where it induces DNA-damage and interferes with repair enzymes.3 Enhances frame shift insertion and deletion in CRISPR genome editing in pluripotent stem cells.4

Conjugation

Unconjugated

Buffer

Off-white solid

Storage Conditions

-20°C

Available Sizes

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