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Retinoic acid

Product Specifications

Background

All−trans−Retinoic acid (ATRA; a metabolite of Vitamin A) is an endogenous ligand for the retinoic acid receptor (RAR) . The binding of retinoic acid to the RAR and retinoid X (RXR) heterodimer causes conformation changes in RAR that affects the binding of other proteins that regulate the growth and differentiation of a variety of both normal and malignant cells.1 ATRA promotes differentiation of embryonic stem cells (ESCs) into a variety of cell types in vitro.2-4

Conjugation

Unconjugated

Buffer

Yellow solid

Storage Conditions

-20°C

Available Sizes

Curated Selection

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