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CD43 Antibody

Mouse monoclonal antibody to CD43 which is the major O-glycosylated cell-surface associated sialoglycoprotein found on the cell membranes of leukocytes. Itbelongs to the surface mucin family which plays a central role in cellular adhesion tumor progression. CD43 is thought to function as a negative regulator of cellular adhesion.

Product Specifications

Product Name Alternative

Leukosialin, Sialophorin, Galactoglycoprotein, GALGP, LSN, SPN, GALGP, GP5

UniProt

P16150

Reactivity

Human

Immunogen

Human T lymphocytes.

Target

CD43

Clonality

Monoclonal

Clone

MEM-59

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Functional application: The antibody MEM-59 activates T lymphocytes and also induces apoptosis in hemopoietic progenitor cells. Flow cytometry: Recommended dilution: 1-5 μg/ml. Immunohistochemistry (paraffin sections) : Positive tissue: spleen, thymus, tonsil; recommended dilution: 10 μg/ml.

Tested Applications

FA, FC, IHC-P, IP, WB

Preservative

Phosphate buffered saline (PBS), pH 7.4

Isotype

Mouse IgG1

Entrez

6693

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