Mirin
Product Specifications
Background
Mirin is an inhibitor of the Mre11-Rad50-Nbs1 (MRN) complex (IC50 = 12 µM for inhibition of ATM activity), part of the MRN-ATM (ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells.
Conjugation
Unconjugated
Buffer
Tan solid
Storage Conditions
-20°C
Available Sizes
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