GW-5074
Product Specifications
Background
Potent inhibitor of cRAF1 kinase (IC50 = 9 nM) . Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects In vivo via a mechanism that is independent of MEK, ERK, and Akt signaling. Cell permeable.
Conjugation
Unconjugated
Buffer
Dark orange solid MP = 267-268°C
Storage Conditions
-20°C
Available Sizes
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