What is the catalog number for CD18 Antibody?

The catalog number for CD18 Antibody is orb154416.

What sizes are available for CD18 Antibody?

CD18 Antibody is available in the following size(s): 0.1 mg.

Is CD18 Antibody in stock?

CD18 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

CD18 Antibody

Mouse monoclonal antibody to CD18 which belongs to the integrin beta chain family. Defects in ITGB2 are the cause of leukocyte adhesion deficiency type 1 (LAD1) . CD18 is involved in cellular adhesion and the immune response. CD18 and the a subunits are expressed broadly by all leukocytes with NK and T cells showing higher density of surface expression.

Product Specifications

Product Name Alternative

Integrin beta2, Complement receptor C3 subunit beta, ITGB2

UniProt

P05107

Reactivity

Human

Immunogen

Leukocytes of a patient suffering from a LGL-type leukemia.

Target

CD18

Clonality

Monoclonal

Clone

MEM-48

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by sequential steps of physicochemical fractionation (caprylic acid precipitation and ammonium sulfate precipitation) .

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Functional application: The antibody MEM-48 induces high-affinity conformation of LFA-1 complex. Western blotting: Recommended dilution: 1-2 μg/ml.Flow cytometry: Recommended dilution: 2 μg/ml. Immunohistochemistry (paraffin sections) : Recommended dilution: 10 μg/ml; positive tissue: spleen, microglia.