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CD79a Antibody

Mouse monoclonal antibody to CD79a which expressed in B-cells. Defects in CD79A are the cause of agammaglobulinemia type 3 (AGM3) . The cytoplasmic tails of CD79A contains an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine

Product Specifications

Product Name Alternative

BCR alpha, Ig-alpha, MB-1, IGA

UniProt

P11912

Reactivity

Bovine, Canine, Equine, Gallus, Guinea pig, Human, Mouse, Porcine, Primate, Rabbit, Rat

Immunogen

Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a

Target

CD79a

Clonality

Monoclonal

Clone

HM47

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Flow cytometry: Recommended dilution: 1-4 μg/ml, intracellular staining.Western blotting: Recommended dilution: 1-2 μg/ml.

Tested Applications

FC, IHC-P, IP, WB

Preservative

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1 kappa

Entrez

973

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