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CD123 Antibody

Mouse monoclonal antibody to CD123 which is also known as IL-3 receptor subunit alpha, IL-3R-alpha and IL3RA, is a single-pass type I membrane protein which is a member of the type I cytokine receptor family and Type 5 subfamily. CD123 is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias. CD123 is also a useful new marker for distinguishing B-cell disorders with circulating villous lymphocytes.

Product Specifications

Product Name Alternative

IL3RA, MGC34174, hIL-3Ra

UniProt

P26951

Reactivity

Human

Immunogen

IL3 receptor alpha chain expressed on the surface of transiently transfected COS cells

Target

CD123

Clonality

Monoclonal

Clone

6H6

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Flow cytometry: Recommended dilution: 1-4 μg/ml.

Tested Applications

FC, IHC-Fr, IP, WB

Preservative

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1

Entrez

3563

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