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Notch1 Antibody

Mouse monoclonal antibody to Notch 1 which belongs to the NOTCH family transmembrane receptors that plays an important role in development and the determination of cell fate. It expressed in fetal tissues most abundant in spleen, brain stem and lung. Notch 1 has functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination.

Product Specifications

Product Name Alternative

AOS5, TAN1, hN1, AOVD1

UniProt

P46531

Reactivity

Human, Mouse

Immunogen

GST fusion protein containing cdc10-NCR region of mouse Notch1

Target

Notch1

Clonality

Monoclonal

Clone

MN1A

Conjugation

Unconjugated

Field of Research

Cardiovascular Research

Purification

Purified by protein-A affinity chromatography.

Concentration

1 mg/ml

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

Flow cytometry: Recommended dilution: 1-4 μg/ml. Intracellular staining.

Tested Applications

FC, ICC, IHC-Fr, IP, WB

Preservative

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Isotype

Mouse IgG1 kappa

Entrez

4851

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