What is the catalog number for CNQX?

The catalog number for CNQX is HY-15066.

What sizes are available for CNQX?

CNQX is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 25 mg, 50 mg, 100 mg.

How many pack sizes does CNQX come in?

CNQX is available in 6 different pack sizes.

CNQX is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CNQX?

CNQX is manufactured by QuantiMol.

What is the estimated delivery time for CNQX?

Estimated delivery time for CNQX is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CNQX?

The safety data sheet for CNQX is available here: http://file.medchemexpress.com/batch_PDF/HY-15066/CNQX-SDS-MedChemExpress.pdf.

CNQX

CNQX (FG9065) is a potent and competitive AMPA/kainate receptor antagonist with IC50s of 0.3 μM and 1.5 μM, respectively. CNQX is a competitive non-NMDA receptor antagonist[1]. CNQX blocks the expression of fear-potentiated startle in rats[5].

Product Specifications

CAS Number

115066-14-3

Product Name Alternative

FG9065

UNSPSC

12352005

Hazard Statement

H410

Target

IGluR

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/CNQX.html

Purity

99.65

Solubility

DMSO : 20 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C(NC2=CC([N+]([O-])=O)=C(C#N)C=C2N1)=O

Molecular Formula

C9H4N4O4

Molecular Weight

232.15

Precautions

H410

References & Citations

[1]T Honoré, et al. Quinoxalinediones: Potent Competitive non-NMDA Glutamate Receptor Antagonists. Science. 1988 Aug 5;241 (4866) :701-3.|[2]Neuman RS, et al. Blockade of excitatory synaptic transmission by 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) in the hippocampus in vitro. Neurosci Lett. 1988 Sep 23;92 (1) :64-8.|[3]Alford S, et al. CNQX and DNQX block non-NMDA synaptic transmission but not NMDA-evoked locomotion in lamprey spinal cord. Brain Res. 1990 Jan 8;506 (2) :297-302.|[4]Pia Bäckström, et al. Attenuation of Cocaine-Seeking Behaviour by the AMPA/kainate Receptor Antagonist CNQX in Rats. Psychopharmacology (Berl) . 2003 Feb;166 (1) :69-76.|[5]Kim M, et al. Infusion of the non-NMDA receptor antagonist CNQX into the amygdala blocks the expression of fear-potentiated startle. Behav Neural Biol. 1993 Jan;59 (1) :5-8.