HDHD4-IN-1

HDHD4-IN-1 (compound 3) is a N-acetylneuraminate-9-phosphate phosphatase (HDHD4) inhibitor (IC50=11 μM) . HDHD4-IN-1 can be used in the study of neurological diseases[1].

Product Specifications

CAS Number

[1447279-68-6]

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hdhd4-in-1.html

Purity

99.95

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=P(O)(O)CC[C@@H](O)[C@H]([C@@]1([H])[C@@H]([C@H](C[C@](O)(O1)C(O)=O)O)NC(C)=O)O

Molecular Formula

C12H22NO11P

Molecular Weight

387.28

References & Citations

[1]Kim S H, et al. Design, synthesis, functional and structural characterization of an inhibitor of N-acetylneuraminate-9-phosphate phosphatase: Observation of extensive dynamics in an enzyme/inhibitor complex[J]. Bioorganic & medicinal chemistry letters, 2013, 23 (14) : 4107-4111.