TGF Beta Receptor Antibody
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS) .
Product Specifications
Specifications
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100
UniProt
P36897
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 134-163 from the human protein was used as the immunogen for this TGF Beta Receptor antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Limitations
This TGF Beta Receptor antibody is available for research use only.
Storage Conditions
Aliquot the TGF Beta Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TGF Beta Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
All species
Image Legend
Western blot analysis of TGF Beta Receptor antibody and Jurkat lysate. Predicted molecular weight: ~55kDa.
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