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Phospho-ERK3 Antibody (pS189)

ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases) . MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

Product Specifications

Specifications

IHC (Paraffin) : 1:50-1:100

UniProt

Q16659

Host

Rabbit

Reactivity

Human

Immunogen

This phospho-ERK3 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS189 of human ERK3.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Limitations

This phospho-ERK3 antibody is available for research use only.

Storage Conditions

Aliquot the phospho-ERK3 antibody (phospho-S189 and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the phospho-ERK3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Chicken, Mouse, Rat

Image Legend

IHC analysis of FFPE human hepatocarcinoma tissue stained with the ERK3 antibody.

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