RUNX2 Antibody

Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex.

Product Specifications

Specifications

IHC (Paraffin) : 1:10-1:50

UniProt

Q13950

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this RUNX2 antibody.

Clonality

Polyclonal

Isotype

Applications

IHC, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Limitations

This RUNX2 antibody is available for research use only.

Storage Conditions

Store at 4°C for up to one month. For long term, aliquot the RUNX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting amounts. Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.