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BRD4 Antibody (N-Terminal Region)

BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t (15;19) (q13; p13.1), which defines an upper respiratory tract carcinoma in young people.

Product Specifications

Specifications

IHC (Paraffin) : 1:50-1:100

UniProt

O60885

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this BRD4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, ELISA

Purity

Purified

Format

Purified

Limitations

This BRD4 antibody is available for research use only.

Storage Conditions

Aliquot the BRD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC analysis of FFPE human breast carcinoma tissue stained with the BRD4 antibody

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