BRD4 Antibody (C-Terminal Region)
BRD4 is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. The gene has been implicated as the chromosome 19 target of translocation t (15;19) (q13; p13.1), which defines an upper respiratory tract carcinoma in young people.
Product Specifications
Specifications
IHC (Paraffin) : 1:50-1:100
UniProt
O60885
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1313-1342 from the human protein was used as the immunogen for this BRD4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, ELISA
Purity
Purified
Format
Purified
Limitations
This BRD4 antibody is available for research use only.
Storage Conditions
Aliquot the BRD4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the BRD4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse
Image Legend
IHC analysis of FFPE human breast carcinoma tissue stained with the BRD4 antibody
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