HHLA2 Antibody / HERV-H LTR-associating protein 2

Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. [UniProt]

Product Specifications

Specifications

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25-1:50

UniProt

Q9UM44

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 58-87 from the human protein were used as the immunogen for the HHLA2 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, FACS

Purity

Antigen affinity purified

Format

Purified

Limitations

This HHLA2 antibody is available for research use only.

Storage Conditions

Aliquot the HHLA2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the HHLA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of human 1) lung, 2) kidney, 3) pancreas, 4) testis and 5) MDA-MB-453 lysate with HHLA2 antibody. Expected molecular weight: 38-60 kDa depending on glycosylation level.